Slimr: independent and evidence first Every diet reviewed against the research

Fasting & meal-timing approaches

Intermittent fasting

Moderate evidence

An umbrella term for alternating periods of eating with periods of fasting or marked energy restriction, including 5:2, alternate-day fasting and time-restricted eating.

What people typically eat

Normal, ideally balanced meals during eating periods; water, black coffee and plain tea during fasts.

What is restricted

When you eat rather than what, though what you eat still determines overall diet quality.

Why people try it

Weight loss without daily calorie counting, plus interest in metabolic and insulin-sensitivity benefits.

Realistic advantages

  • Simple rules, many people find "when" easier than "what"
  • Trials show weight loss comparable to daily calorie restriction
  • The 5:2 pattern has been shown to improve insulin resistance

Realistic disadvantages

  • Hunger, headaches and poor concentration during adaptation
  • No demonstrated long-term superiority over ordinary calorie control
  • Easy to overeat in the eating window and cancel the deficit

Strength of evidence

Moderate evidence

Growing trial base showing equivalence with standard calorie restriction; unique long-term benefits are unproven.

Key studies

  • Trepanowski et al., JAMA Internal Medicine, 2017. Alternate-day fasting produced similar weight loss to daily calorie restriction, with higher dropout rates.
  • TREAT trial: Lowe et al., JAMA Internal Medicine, 2020. A 16:8 eating window on its own produced no significant extra weight loss against three structured meals a day.

Likely cost and difficulty

Low cost; moderate-to-high difficulty during fasting periods.

Nutritional risks

Low for healthy adults; risk of undernutrition if eating windows are used badly.

Who should avoid it

Pregnancy, under-18s, eating-disorder history, and people on glucose-lowering medication without medical advice.

Is professional supervision advisable?

Advisable if you have diabetes or take medication that requires food.

References

Written by the Slimr editorial team. How we review diets.

Illustration for the Intermittent fasting review on Slimr

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